Table 1.
Performed solubility measurements of nicotinamide (NA), succinic acid (SA) and mixtures of both in solvents or solvent/anti-solvent mixtures at specific temperatures.
| Component(s) | Solvent or Solvent/Anti-Solvent Mixture | Temperature(s) (K) |
|---|---|---|
| NA | ethanol | 293.15, 298.15, 303.15, 310.15, 318.15 |
| NA | ethyl acetate | 298.15, 310.15 |
| NA | acetonitrile | 288.15, 298.15, 303.15, 310.15 |
| NA | ethanol/ethyl acetate mixtures (0.75/0.25 w/w, 0.5/0.5 w/w, and 0.25/0.75 w/w) |
298.15 |
| NA | ethanol/ethyl acetate mixtures (0.5/0.5 w/w, and 0.25/0.75 w/w) |
310.15 |
| NA | ethanol/water mixture (0.5/0.5 w/w) | 298.15 |
| NA | ethanol/acetonitrile mixture (0.67/0.33 w/w) | 298.15 |
| SA | ethyl acetate | 293.15, 298.15, 303.15, 310.15, 318.15 |
| SA | ethanol/ethyl acetate mixtures (0.75/0.25 w/w, 0.5/0.5 w/w, and 0.25/0.75 w/w) |
298.15 |
| SA | ethanol/ethyl acetate mixtures (0.5/0.5 w/w, and 0.25/0.75 w/w) |
310.15 |
| SA | ethanol/water mixture (0.5/0.5 w/w) | 298.15 |
| SA | ethanol/acetonitrile mixture (0.67/0.33 w/w) | 298.15 |
| NA, SA | ethyl acetate | 298.15 |
| NA, SA | acetonitrile | 298.15 |
| NA, SA | ethanol | 298.15, 310.15 |
| NA, SA | ethanol/ethyl acetate mixtures (0.75/0.25 w/w, 0.5/0.5 w/w, and 0.25/0.75 w/w) |
298.15 |
| NA, SA | ethanol/ethyl acetate mixtures (0.5/0.5 w/w, and 0.25/0.75 w/w) |
310.15 |
| NA, SA | ethanol/water mixture (0.5/0.5 w/w) | 298.15 |
| NA, SA | ethanol/acetonitrile mixture (0.67/0.33 w/w) | 298.15 |