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Thrombus formation in acute coronary syndrome by the dual pathway: platelet activation/aggregation and fibrin formation. Thrombin links vascular injury, platelet activation and the conversion of fibrinogen to fibrin. ADP = adenosine diphosphate, F = factor, GP = glycoprotein, α2β = integrin α2β, TF = tissue factor, TXA2 = thromboxane A2, PAR = protease activated receptor, vWF = von Willebrand factor.
