Table 1.

Identification of the five active PfTrxR inhibitors.

Compound Number	MMV	IUPAC Name
1	MMV006278	2-ethyl-1,3-dimethylquinolin-4-imine;hydroiodide
2	MMV085203	2-(2-methoxyanilino)-3-piperidin-1-ylnaphthalene-1,4-dione
3	MMV008956	5-chloro-4-(6,7-diethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-2-methoxyphenol
4	MMV396797	7-amino-3-(3,4-dimethoxyphenyl)-2-methylpyrazolo[1,5-a]pyrimidine-6-carbonitrile
5	MMV008416	3-ethyl-1-methyl-2-propylquinolin-4-imine;hydron;iodide