Table 4.
Classes a | Only Aromatic Rings | Only Non-Aromatic Rings | Both Aromatic and Non-Aromatic Rings | No Rings | Bridge Rings |
---|---|---|---|---|---|
All drugs | 37.5 (12.1, 16.5) b | 12.4 | 42.0 (11.1, 11.8) c | 5.8 | 2.4 |
Oral drug | 36.9 (11.1, 15.9) b | 11.1 | 45.2 (11.6, 12.4) c | 4.1 | 2.3 |
CNS drugs | 31.7 (8.8, 18.3) b | 7.0 | 53.6 (12.0, 17.4) c | 5.3 | 2.4 |
Cardiovascular drugs | 42.0 (14.1, 17.3) b | 7.3 | 45.3 (12.8, 12.3) c | 3.6 | 1.7 |
Anti-infective drugs | 37.8 (10.5, 17.3) b | 15.9 | 41.5 (13.0, 11.9) c | 3.3 | 1.4 |
Anti-cancer drugs | 30.1 (9.5, 7.7, 7.9) d | 13.3 | 43.7 (6.6, 6.8, 5.0) e | 11.1 | 1.8 |
a The captions in each row represent drugs containing different rings; b The numbers in brackets represents the proportions of drugs with one aromatic ring and two aromatic rings, sequentially; c The numbers in brackets represents the proportions of drugs with one aromatic ring and one non-aromatic ring, two aromatic rings and one non-aromatic ring, sequentially; d The numbers in brackets represents the proportions of drugs with one aromatic ring, two aromatic rings and three aromatic rings, sequentially; e The numbers in brackets represents the proportions of drugs with two aromatic rings and one non-aromatic ring, two aromatic rings and two non-aromatic rings, two aromatic rings and three non-aromatic rings, sequentially.