Table 1.
Antibacterial and Antifungal Activities of the Synthesized Compounds.
| Microorganisms | Compound Tested | Standard (30 µg/mL) | |||
|---|---|---|---|---|---|
| 5a | 5b | 5d | 5e | ||
| Fungi | Itraconazole | ||||
| Aspergillus fumigatus (RCMB 002003) | 18.2 ± 0.84 | 11.3 ± 0.68 | 21.1 ± 0.2 | 16.3 ± 0.09 | 22 ± 0.1 |
| Geotrichumcandidum (RCMB 052006) | 18.9 ±0.35 | 12.6 ±0.54 | 19.3 ± 0.05 | 15.4 ± 0.1 | 26 ± 0.3 |
| Syncephalastrum racemosum (RCMB 005003) | 11.2 ± 0.44 | NA | 16.4 ± 0.08 | 14.2 ± 0.05 | 19 ± 0.1 |
| Candida albicans (RCMB 005002) | NA | NA | NA | NA | 24 ± 0.1 |
| Gram-positive Bacteria | Penicillin G | ||||
| Staphylococcus aureus (RCMB 000106) (MSSA) | 17.8 ± 0.58 | 10.7 ± 0.36 | 21.4 ± .03 | 17.9 ± 0.03 | 27.4 ± 0.08 |
| Bacillis subtilis (RCMB 000107) | 17.9 ± 0.46 | 11.1 ± 0.72 | 26.1 ± 0.04 | 15.2 ± 0.04 | 28.6 ± 0.03 |
| Gram-negative Bacteria | Streptomycin | ||||
| Pseudomonas aeruginosa (RCMB 000102) | NA | NA | 19.9 ± 0.09 | NA | 26.3 ± 0.03 |
| Escherichia coli (RCMB 000103) | 12.6 ± 0.57 | 12.4 ±0.04 | 17.2 ± 0.2 | 13.4 ± 0.04 | 30.1 ± 0.07 |
NA: No activity, data are expressed in the form of mean ± standard deviation (S.D.)