Table 1.
IC50 values of compounds 1–13 against scavenging DPPH radicals or inhibition of NO production on LPS-stimulated RAW264.7 cells.
| Samples | IC50 (μM) a | |
|---|---|---|
| DPPH Radical Scavenging Activity | NO Production Inhibitory Activity | |
| 1 | 31.17 ± 0.31 | 100< |
| 2 | 23.64 ± 1.26 | 100< |
| 3 | 24.08 ± 0.90 | 100< |
| 4 | 66.45 ± 5.79 | 100< |
| 5 | 31.71 ± 1.42 | 100< |
| 6 | 9.47 ± 0.42 | 100< |
| 7 | 28.39 ± 1.68 | 100< |
| 8 | 20.98 ± 1.10 | 100< |
| 9 | 8.45 ± 1.99 | 28.59 ± 0.82 |
| 10 | 6.72 ± 0.16 | 98.74 ± 8.91 |
| 11 | 6.01 ± 0.16 | 20.99 ± 0.14 |
| 12 | 5.40 ± 0.16 | 20.93 ± 0.15 |
| 13 | 5.52 ± 0.28 | 21.26 ± 0.38 |
| Vit.C b | 13.30 ± 0.31 | - |
| l-NMMA b | - | 17.10 ± 0.25 |
a Values are presented as the mean ± SD (n = 3); b Positive controls. Vit.C: l-ascorbic acid; l-NMMA: NG-monomethyl-l-arginine.