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Effect of compound 9a on scPTZ-induced seizures in mice (i.p.).
| Compound | Doses (mg/kg) | Clonic Seizures (%) a | Tonic Seizures (%) | Lethality (%) |
|---|---|---|---|---|
| DMSO | - | 100 | 100 | 90 |
| 9a | 100 | 100 | 10 | 60 |
| Carbamazepine | 50 | 100 | 0 | 0 |
a The number of mice with clonic seizures, tonic seizures, and deaths/the number of animals tested ×100%.
