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Pharmacokinetic parameters of compound 9a.
| Compound | MW a (< 500) | HBA b (< 10) | HBD c (≤ 5) | TPSA d | %ABS e |
|---|---|---|---|---|---|
| 9a | 287.36 | 5 | 1 | 59.92 | 88.33 |
a MW: molecular weight; b HBA: number of hydrogen bond acceptors; c HBD: number of hydrogen bond donors; d TPSA: topological polar surface area; e %ABS: percentage of absorption.
