Table 3.
Resolution of racemates on PPAA-Val and PPAA-Val-H a.
| Racemates | PPAA-Val | PPAA-Val-H | ||||||
|---|---|---|---|---|---|---|---|---|
| Coating solvent: DMF | Coating Colvent: THF | Coating Solvent: CHCl3 | Coating Solvent: DMF | |||||
| k1′ | α | k1′ | α | k1′ | α | k1′ | α | |
| 1 | 0.19 | 1.00 | 0.05 | 1.00 | 0.13 | 1.00 | 0.11 | 1.00 |
| 2 | 0.44 (−) | 2.18 | 0.13 (−) | 2.15 | 0.24 | 1.00 | 1.14 | 1.00 |
| 3 | 0.65 | 1.00 | 0.18 | 1.00 | 0.33 | 1.00 | 0.36 | 1.00 |
| 4 | 1.67 | 1.00 | 0.58 | 1.00 | 0.84 | 1.00 | 0.99 | 1.00 |
| 5 | 13.54 (+) | ~1 | 13.12 (+) | ~1 | 4.33 | 1.00 | 5.80 | 1.00 |
| 6 | 0.36 (−) | 2.60 | 0.12 (−) | 2.25 | 0.29 (−) | 2.01 | 0.92 | 1.00 |
| 7 | 4.83 | 1.00 | 1.58 | 1.00 | 2.18 | 1.00 | 1.99 | 1.00 |
| 8 | 2.26 | 1.00 | 0.67 | 1.00 | 1.12 | 1.00 | 1.19 | 1.00 |
a Column: 25 cm × 0.2 cm i.d.; Eluent:hexane-2-propanol (90/10, v/v); Flow rate: 0.1 mL/min; The signs in parentheses represent the optical rotation of the first-eluted enantiomer.