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. 2016 Jun 11;21(6):752. doi: 10.3390/molecules21060752

Table 3.

Activities of bLfcin against different bacterial, fungal and parasite species. References from [14].

Gram Positive MIC (µg/mL) Gram Negative MIC (µg/mL)
Bacillus subtilis ATCC 6633 0.6–2 Escherichia coli IID-861 6–50
B. subtilis 2116 7.8 E. coli ATCC 25922 3.3–30
B. subtilis IFO-3009 2 E. coli O111 6–12
B. cereus MMI-272 9 E. coli O157:H7-A 8
B. cereus 6349 15.6 E. coli O157:H7-B 8
B. circulans JCM-2504T 0.6 E. coli O157:H7-C 10
B. sphaericus 7585 1.9 E. coli O157:H7-D 8
Staphylococcus aureus JCM-2151 6-25 E. coli O157 wild type 7.8
S. aureus JCM-2179 6 E. coli CL99 1–2 4
S. aureus JCM-2413 18 E. coli K12 UB1005 1.6
S. aureus ATCC 25923 30 E. coli K12 UB1005 DC-2 1.6
S. aureus ATCC 29213 6.6 E. coli 7275 7.8
S. aureus 8530 15.6 E. coli 10418 3.9
S. aureus 8532 15.6 E. coli wild type 15.6–31.2
S. aureus R1 (antib-res) 12 Pseudomonas aeruginosa MMI-603 12–24
S. epidermidis JCM-2414T 3–6 P. aeruginosa IFO-3445 12–18
S. epidermidis 4276 7.8 P. aeruginosa IFO-3446 24
S. haemolyticus JCM-2416T 1 P. aeruginosa IFO-3448 45
S. hominus JCM-2419T 3 P. aeruginosa IFO-3452 30
S. sp. wild type 7.8–15.6 P. aeruginosa ATCC-2783 3.3
Listeria monocytogenes IDF-Ib 0.6 P. aeruginosa PAO 3.3
L. monocytogenes JCM-7673 1 P. aeruginosa 10662 31.2
L. monocytogenes JCM-7674 3 P. aeruginosa wild type 15.6–31.2
L. monocytogenes EGD 1.6 P. putida wild type 15.6
L. monocytogenes 4b 6.6 P. cepacia wild type 250–500
L. monocytogenes 5105 1.9 P. fluorescens wild type 15.6
Streptococcus bovis JCM-5672 3–6 Pseudomonas fluorescens IFO-14160 >60
S. mutans JCM-5705T 6 Salmonella enteritidis IID-604 12–18
S. mutans JCM-5175 6 S. typhimurium SH7641 1.6
S. mutans JCM-5176 3 S. typhimurium SL696 5
S. thermophilus ATCC-19258 3 S. typhimurium 6749 1.6
S. lactis ATCC-19435 3 S.montevideo SL5222 3
S. cremoris ATCC-9265 3 S. newport 5751 7.8
Lactobacillus. casei MMI-114 12 S. typhi wild type 7.8–15.6
Corynebacterium ammoniagenes JCM-1306 0.3 S. enteritidis wild type 7.8
C. renale JCM-1322 1 Yersinia enterocolitica IID-981 6–24
C. diphtheriae JCM-1310 18 Y. enterocolitica wild type 62.5
Clostridium perfringens ATCC-6013 24 Proteus vulgaris JCM 1668T 12–45
C. paraputrificum MMI-25 3 P. vulgaris wild type 500
Micrococcus sp. wild type 7.8–31.2 P. vulgaris 4635 500
Bifidobacterium adolescentis ATCC-15703 no P. mirabilis wild type 250–500
B. breve ATCC-15700 no P. mirabilis NCTC-60 >200
B. longum ATCG15707 no P. mirabilis ATCC 35659 >1000
B. infantis ATCC-15697 no P. rettgeri wild type 250
B. bifidum ATCC-15696 >60 × 103 P. sp. wild type 500
Klebsiella pneumoniae 418 500 Klebsiella pneumoniae JCM 1662T 9
Enterococcus faecalis ATCCE 19433 >60 K. pneumoniae JCM-16623 12
Enterococcus sp. wild type 62.5–125 K. pneumoniae 5055 15.6
K. pneumoniae wild type 15.6–62.5
K. pneumoniae 418 500
Shigella flexneri 5452 3.9
Shigella flexneri wild type 3.9
Shigella sonnei wild type 7.8
Enterobacter intermedius wild type 15.6
Enterobacter aerogenes wild type 125
Enterobacter cloacae wild type 70.3
Enterobacter sp. wild type 7.8
Serratia sp. wild type 500
S. marcescens wild type 500
S. liquefaciens wild type 500
Citrobacter freundii wild type 7.8–62.5
C. diversus wild type 62.5
Bacteroides distasonis MMI-M602 no
B. vulgatus MMI-S601 no
Yeast MIC (µg/mL) Filamentous Fungi MIC (µg/mL)
Candida. albicans TIMM 0154 25 Trichophyton mentagrophytes TIMM 1189 12
Candida albicans TIMM 1768 12.5–400 T. mentagrophytes TIMM 2789 6.3
C. albicans TIMM 3164 400 T. mentagrophytes IFO 5466 30
C. albicans TIMM 3315 50 T. mentagrophytes IFO 5812 30
C. albicans TIMM 3317 200 T. mentagrophytes IFO 5974 45
C. albicans JCM1542T 24 T. mentagrophytes 5
C. albicans JCM2072 30 T. rubrum IFO 6203 24
C. albicans JCM2075 45 T. rubrum IFO 32409 13
C. albicans JCM2076 24 T. tonsurans 5–40
C. albicans JCM2374 24 T. violaceum 40
C. albicans JCM2900 24 T. rubrum >80
C. albicans JCM2901 45 T. shoenleinii >80
C. albicans JCM2902 60 Nannizzia incurvata JCM 1906 18
C. albicans JCM2904 45 N. otae JCM 1909 60
C. albicans 6372 0.8 N. gypsea JCM 1903 >60
C. albicans 6434 0.8 Penicillium pinophilum JCM 5593 45
C. albicans ATCC 90028 400 P. vermiculatum JCM 5595 45
C. albicans wild type 7.8–21.67 P. notatum >80
C. parapsilosis wild type 7.8–80 P. expansum >80
C. tropicalis 0.31–1.25 Aspergillus versicolor 10
C. glabrata 120 A. fumigatus JCM 1917 >60
C. guilliermondii A. niger JCM 5546 >60
C. kefyr 2.5–10 A. fumigatus >80
C. krusei 10–20 A. niger >80
Cryptococcus uniguttulatus JCM 3685 6 A. flavus >80
C. curvatus JCM 1532T 9 A. clavatus >80
C. albidus JCM 8252 24 Fusarium moniliforme 2.5–5
C. neoformans 0.63 Absidia corymbifera 40
Trichosporon cutaneum JCM 2466 18 Microsporum canis 40
T. cutaneum 1.25–2.5 M. gypseum 20–40
Saccharomyces cerevisiae 0.63 Epidermophyton floccosum 0.31-2.5
Fonsecaea pedrosoi 5
Exophiala dermatitidis 2
Phialophora verrucosa 5–10
Cladosporium trichoides 0.63–1.2
Paracoccidioides brasiliensis 5
Sporothrix schenckii 2–10
Rhizopus oryzae JCM 5557 >60
Mucor circinelloides >80
M. racemosus >80
Parasite LD50 (µM)
Giardia lamblia 2.8
Entamoeba histolytica 647
Toxoplasma gondii no