Table 2.
Levels of RNs in HepG2 cells of every group (pmol/106 cell).
| MRM Transition | Control | F | P | P-F | |
|---|---|---|---|---|---|
| ATP | 506.0→159.0 | 10904.7 ± 275.1 | 18975.6 ± 1728.7 ** | 9775.0 ± 936.9 * | 16173.0 ± 1784.1 **,# |
| ADP | 426.0→328.0 | 2985.5 ± 89.5 | 49033 ± 207.5 ** | 2933.1 ± 190.5 | 4916.2 ± 709.2 ** |
| AMP | 346.0→79.3 | 469.5 ± 21.1 | 608.5 ± 49.7 ** | 444.1 ± 27.6 | 823.9 ± 156.21 **,## |
| CTP | 482.0→384.0 | 1601.3 ± 41.7 | 2860.0 ± 269.9 ** | 1523.9 ± 162.1 | 2116.5 ± 213.2 **,## |
| CDP | 402.0→159.0 | 430.3 ± 15.9 | 707.9 ± 35.9 ** | 468.4 ± 28.9 * | 697.7 ± 98.7 ** |
| CMP | 322.0→79.4 | 153.4 ± 7.01 | 200.2 ± 7.2 ** | 148.3 ± 8.6 | 232.2 ± 37.0 **,# |
| GTP | 522.0→423.9 | 5428.2 ± 110.7 | 8923.2 ± 807.2 ** | 4668.0 ± 547.8 ** | 7912.1 ± 807.8 **,# |
| GDP | 442.0→344.0 | 1263.4 ± 45.3 | 1935.3 ± 64.0 ** | 1203.3 ± 87.2 | 1858.9 ± 305.0 ** |
| GMP | 362.0→79.30 | 67.0 ± 2.8 | 81.3 ± 8.2 ** | 55.0 ± 4.1 ** | 115.8 ± 22.5 **,## |
| UTP | 482.9→385.0 | 4989.0 ± 114.2 | 8858.3 ± 774.9 ** | 5097.9 ± 517.1 | 7045.6 ± 741.2 **,## |
| UDP | 403.0→159.0 | 792.9 ± 38.2 | 1280.0 ± 69.9 ** | 844.9 ± 55.7 | 1261.1 ± 189.2 ** |
| UMP | 323.0→79.3 | 39.3 ± 1.8 | 49.0 ± 4.2 ** | 38.6 ± 2.3 | 56.4 ± 12.4 ** |
Note: All data are expressed as mean ± SD values by three independent experiments. P values of less than 0.05 (* p < 0.05, ** p < 0.01, versus the control group; # p <0.05, ## p < 0.01, compared with the 5-FU group) are considered significant.