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Immunohistochemical localization of insulin-like growth factor-1 and bone morphogenetic protein-2 on the proximal tibial growth plate in rats, control: vehicle treated control group, rhGH: rhGH 200 μg/kg (s.c.) treated group, P. umbrosa: P. umbrosa 300 mg/kg (p.o.) treated group, RZ: resting zone, PZ: proliferative zone, HZ: hypertrophic zone. The scale bar is 100 μm.
