Figure 7.

The effects of HJB-1 pretreatment on NF-κB activation in the lung tissues of LPS-induced ARDS mice. HJB-1 (2 and 10 mg/kg, i.p.) or Dex (5 mg/kg, i.p.) was given 1h before LPS treatment. Lung tissues were collected 24 h after LPS treatment and (a) IκB-α degradation; (b) NF-κB p65 subunit in nuclear extracts were examined by Western blot. The relative quantificationof target proteins was calculated by comparison of the band density levels between samples. The values shown in the graphs represent the mean ± SEM (n = 6). ### p < 0.001 vs. control group; * p < 0.05, ** p < 0.01 and *** p < 0.001 vs. LPS group.