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. 2016 Mar 1;21(3):123. doi: 10.3390/molecules21030123

Figure 7.

Figure 7

Fluorescent micrographs of AO/PI double stained HeLa cells that were treated with were 4.75 ± 1.23 μg/mL SG-stabilized AuNPs; (a) Untreated cells showing normal cell structures; (b) Treated cells after 24 h incubation showing membrane blebbing and chromatin condensation; (c) Membrane blebbing, chromatin condensation and nuclear margination with early apoptotic cells after 48 h treatment; (d) Membrane blebbing, chromatin condensation and apoptotic body formation with numerous late apoptotic cells after 72 h treatment. VC: Viable cells, EA: Early apoptotic cells, CC: Chromatin condensation, BL: Membrane blebbing, MN: Marginated nucleus, LA: Late apoptotic cells, and AB: Apoptotic body (400× magnification).