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Molecular mechanisms mediated by β-CDs in Alzheimer’s, Parkinson’s, Hugtington’s, Niemann-Pick Type C diseases. Niemann-Pick Type C disease is characterized by intracellular accumulation of unesterified cholesterol and glycosphingolipids. Alzheimer’s, Parkinson’s and Huntington’s diseases are charaterized by abnormal aggregation of peptides leading to the neurodegenerative processes. β-CD family acts at several levels and shows beneficial effects in these neurodegenerative diseases.
