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. 2016 Feb 27;21(3):277. doi: 10.3390/molecules21030277

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© 2016 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of L. obtusiloba extracts on c-Fos expression in the CA3 region of the hippocampus. Representative photomicrographs show c-Fos–positive nuclei in the CA3 of normal (non-exposed to FST) (a); control (b); RU 486 (10 mg/kg)-treated (c); and L. obtusiloba extracts (200 mg/kg)-treated (d) rats exposed to the FST. Arrows indicate examples of c-Fos positive neurons. Columns show the means ± SEMs (n = 5) values of c-Fos expression in the CA3 region of the hippocampus (e). These data were evaluated by Kruskal-Wallis median test (p < 0.01) and validated by the Dunn’s multiple comparison test (p < 0.05). * p < 0.05 vs. the control group. ^## p < 0.01 vs. the non-exposed to FST.