Table 3.
Inhibitory effect of isolated compounds from X. strumarium on α-glucosidase.
| Entry | Products | Concentration (μg/mL) | Inhibition (%) | IC50 1 (μg/mL) |
|---|---|---|---|---|
| Acarbose 2 | 1000 | 106.14 | 377.19 ± 37.8 (584.79 μM) | |
| 500 | 60.29 | |||
| 250 | 41.06 | |||
| 50 | 16.98 | |||
| 1 | Protocatechuic acid | 50 | 17.45 | - |
| 2 | 3-Hydroxy-1-(4-hydroxy phenyl) propan-1-one | 50 | 8.60 | - |
| 3 | Cytidine | 50 | 4.70 | - |
| 4 | Neochlorogenic acid methyl ester | 50 | - | - |
| 5 | Chlorogenic acid | 50 | 6.60 | - |
| 6 | Methyl-3,5-di-O-caffeoylquinic acid | 25 | 96.50 | 9.78 ± 0.79 (18.42 μM) |
| 12.5 | 59.11 | |||
| 5 | 40.00 | |||
| 2.5 | 22.63 | |||
| 7 | Thiazine-3,5-dione-11-O-glucopyranoside | 50 | 10.18 | - |
| 8 | Patuletin-3-glucuronide | 50 | 6.11 | - |
| 9 | Quercetin-3-O-glucuronide | 50 | 15.40 | - |
| 10 | 3,5-di-O-caffeoylquinic acid | 100 | 99.44 | 45.48 ± 4.52 (88.14 μM) |
| 50 | 52.85 | |||
| 25 | 33.72 | |||
| 5 | 9.34 | |||
| 11 | 1,5-di-O-caffeoylquinic acid | 50 | 46.20 | - |
| 12 | 1,3-di-O-caffeoylquinic acid | 50 | 38.37 | - |
| 13 | 1,3,5-tri-O-caffeoylquinic acid | 50 | 22.05 | - |
| 14 | Raffinose | 50 | 5.82 | - |
1 The IC50 value was defined as the half-maximal inhibitory concentration and mean of 3 duplication analyses of each sample. 2 Acarbose was used as the positive control. - is no activity.