Table 5.
Inhibitory effect of isolated compounds from X. strumarium on advanced glycation end products (AGEs).
| Entry | Products | Concentration (μg/mL) | Inhibition (%) | IC50 1 (μg/mL) |
|---|---|---|---|---|
| Aminoguanidine 2 | 400 | 98.17 | 155.88 ± 15.45 (1410.00 μM) | |
| 200 | 61.01 | |||
| 100 | 37.84 | |||
| 50 | 27.97 | |||
| 1 | Protocatechuic acid | 100 | 9.49 | - |
| 2 | 3-Hydroxy-1-(4-hydroxy phenyl) propan-1-one | 100 | 8.50 | - |
| 3 | Cytidine | 100 | 33.16 | - |
| 4 | Neochlorogenic acid methyl ester | 100 | 11.40 | - |
| 5 | Chlorogenic acid | 100 | 7.47 | - |
| 6 | Methyl-3,5-di-O-caffeoylquinic acid | 100 | 89.47 | 43.96 ± 3.89 (82.79 μM) |
| 50 | 54.77 | |||
| 20 | 34.59 | |||
| 10 | 24.24 | |||
| 7 | Thiazine-3,5-dione-11-O-glucopyranoside | 100 | 22.24 | - |
| 8 | Patuletin-3-glucuronide | 100 | 6.11 | - |
| 9 | Quercetin-3-O-glucuronide | 100 | 23.96 | - |
| 10 | 3,5-Di-O-caffeoylquinic acid | 100 | 42.91 | - |
| 11 | 1,5-Di-O-caffeoylquinic acid | 100 | 25.04 | - |
| 12 | 1,3-Di-O-caffeoylquinic acid | 100 | 40.19 | - |
| 13 | 1,3,5-Tri-O-caffeoylquinic acid | 100 | 40.22 | - |
| 14 | Raffinose | 100 | 14.99 | - |
1 The IC50 value was defined as the half-maximal inhibitory concentration and mean of 3 duplication analyses of each sample. 2 Aminoguanidine was used as the positive control. - is no activity.