Table 1.
Effect of TAU or SF on the serum and hepatic iron concentration, liver-to-body weight ratio, serum levels of ALT and AST in iron-overloaded mice.
| Group | Control | Iron | Iron + TAU | Iron + SF |
|---|---|---|---|---|
| Serum iron concentration (μmol/L) | 35.03 ± 1.26 | 415.26 ± 14.21 a | 395.18 ± 15.18 a | 398.64 ± 16.21 a |
| Hepatic iron concentration (mg/g dry weight) | 0.058 ± 0.002 | 1.102 ± 0.032 a | 1.081 ± 0.029 a | 1.076 ± 0.031 a |
| LW/BW (mg/g) | 45.6 ± 2.2 | 102.6 ± 4.3 a | 62.3 ± 2.2 a,b | 65.1 ± 2.6 a,b |
| ALT (U/L) | 46.82 ± 1.35 | 235.21 ± 8.62 a | 120.32 ± 4.61 a,b | 135.06 ± 5.25 a,b |
| AST (U/L) | 100.65 ± 3.25 | 405.28 ± 13.06 a | 224.52 ± 9.31 a,b | 240.61 ± 9.53 a,b |
Note: Data are expressed as the mean ± the standard error of the mean (n = 12). a p < 0.01 vs. Control group; b p < 0.01 vs. Iron group. ALT, alanine transaminase; AST, aspartate transaminase.