Scheme 1.
Synthetic route to ciprofloxacin-nitroxide hybrid 10 and its corresponding methoxyamine derivative 11. Reagent and conditions: (a) (i) AcOH, MeOH 60 °C, 2 h. (ii) NaBH3CN, 50 °C, 24 h; (b) 2 M NaOH, MeOH, 50 °C, 5 h.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.