Figure 6.

The analgesic activity results using hot-plate test for control, compound 12–19, and ibuprofen at 0.24 (${}^{▄}$) and 0.48 mmol/kg (${}^{▄}$); data were represented as means ± SEM, n = 6; data were analyzed by One way ANOVA followed by student-Newman-Keuls multiple comparison test; % change = 100 × (T₁ − T₀)/T₀; ^a statistically significant from control (p < 0.001); ^b statistically significant from control (p < 0.01); ^c statistically significant from control (p < 0.05); ^d statistically not significant from control.