Table 1.
MICs of tebipenem pivoxil and other antibiotics against tested Gram-positive bacteria.
Strain | MIC50/MIC90 (μg/mL) | |||
---|---|---|---|---|
Tebipenem Pivoxil | Meropenem | Imipenem and Cilastatin | Ceftriaxone | |
MSSA | ≤0.125/0.125 | ≤0.125/0.25 | ≤0.125/2 | 2/4 |
MRSA | 8/16 | 16/32 | 32/128 | >128/>128 |
MSSE | ≤0.125/0.5 | ≤0.125/1 | ≤0.125/1 | 1/16 |
MRSE | 8/8 | 16/16 | 16/64 | 64/>128 |
Enterococcus faecalis | 0.25/32 | 2/>128 | 4/>128 | 32/>128 |
Enterococcus faecium | 64/128 | >128/>128 | >128/>128 | >128/>128 |
Pyogenic streptococcus | ≤0.125/≤0.125 | ≤0.125/≤0.125 | ≤0.125/0.25 | 4/8 |