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Incidence of toxicity in liver and kidney after oral administration of tebipenem pivoxil.
| Reagent | Dosage (g/kg) | Liver Toxicity | Kidney Toxicity | ||
|---|---|---|---|---|---|
| Present | Absent | Present | Absent | ||
| Tebipenem pivoxil | 4.00 | 6 | 13 | 5 | 14 |
| 3.20 | 4 | 16 | 4 | 16 | |
| 2.89 | 3 | 17 | 2 | 18 | |
| Vehicle | - | 0 | 0 | 0 | 0 |
