Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jan 13;21(1):81. doi: 10.3390/molecules21010081

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Effect of TXA1·HCl treatment in MCF-7cell death, analyzed with the TUNEL assay. Cells were treated for 24, 48 and 72 h with medium only (Blank), H₂O and TXA1·HCl (5, 10 and 20 µM). (a) Representative fluorescence microscopy images showing increasing TUNEL-positive cells (green) as induced by 5, 10 or 20 µM of TXA1·HCl, while few or no TUNEL-positive cells were observed in control cultures (Blank and H₂O). DNA was stained with DAPI (blue); bar = 40 μm; (b) Quantification of the levels of cell death. Results are the mean ± SEM from at least three independent experiments. * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001; **** p ≤ 0.0001 when comparing treatment vs. control (H₂O).

Effect of TXA1·HCl treatment in MCF-7cell death, analyzed with the TUNEL assay. Cells were treated for 24, 48 and 72 h with medium only (Blank), H₂O and TXA1·HCl (5, 10 and 20 µM). (a) Representative fluorescence microscopy images showing increasing TUNEL-positive cells (green) as induced by 5, 10 or 20 µM of TXA1·HCl, while few or no TUNEL-positive cells were observed in control cultures (Blank and H₂O). DNA was stained with DAPI (blue); bar = 40 μm; (b) Quantification of the levels of cell death. Results are the mean ± SEM from at least three independent experiments. * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001; **** p ≤ 0.0001 when comparing treatment vs. control (H₂O).