Table 3.
In vitro cytotoxic activities of title compounds.
| Compound | Cell Lines (IC50, μM) a | ||
|---|---|---|---|
| A549 | Hela | SGC7901 | |
| 5 | >40 | >40 | 27.24 |
| 6 | >40 | 32.53 | >40 |
| 7 | >40 | >40 | >40 |
| 8 | >40 | >40 | >40 |
| 9 | 19.27 | >40 | >40 |
| 10 | >40 | >40 | >40 |
| 11 | 16.14 | 8.57 | >40 |
| 12 | >40 | 25.14 | 16.27 |
| 13 | >40 | >40 | 25.04 |
| 14 | >40 | 33.24 | >40 |
| 15 | >40 | 22.36 | 30.43 |
| 16 | 0.12 | 26.32 | 2.75 |
| 17 | 27.82 | >40 | 15.41 |
| 18 | 19.34 | >40 | 23.92 |
| 19 | 6.25 | 18.71 | 36.23 |
| 20 | 8.11 | 28.74 | >40 |
| 21 | 23.22 | 15.35 | >40 |
| 22 | 26.07 | >40 | >40 |
| 23 | 34.13 | 12.68 | 7.45 |
| 24 | >40 | 27.58 | >40 |
| 25 | >40 | 26.22 | >40 |
| DDP | 11.54 | 20.52 | 12.44 |
a Cytotoxicity as IC50 values for each cell line, the concentration of compound that inhibits 50% of the cell growth measured by MTT assay. DDP: cisplatin.