Figure 6.

Structure of the hsGS, zmGS and mtGS double ring (a) or single ring (b) oligomers showing: (a1) top view; (a2) side view; (a3) highlight of the inter-ring contact surface between one monomer A of the above ring and the lower ring monomers, defined by all residues of the monomer A (cyan)/lower ring monomers (blue) that are within 5 Å distance from each other; (b1) ring top view with distinct monomers highlighted by colour; (b2) the active site location in between two adjacent monomers is demonstrated by a yellow surface delimiting the binding area of glutamate, ATP and metal ions; and (b3) highlight of the intra-ring contact surface between monomer A and the adjacent monomers of the same ring, with the residues of monomer A within 5 Å distance from the adjacent monomers coloured in cyan and the residues, also within 5 Å, of the adjacent monomers to monomer A coloured in blue.