Table 1.

Residues detected on hsGS PPI as a potential HS (buried area ≥ 40 Ų in at least 6 monomers) with the respective mean value of ΔΔG_bind determined by cASM, standard error of mean (SEM) and their classification as HS (red), WS (orange) or NS (yellow).

Resid	ΔΔGbind	SEM	Classif
I13	3.82	0.40	WS
K14	2.67	0.29	WS
Y17	2.69	0.16	WS
M18	0.59	0.22	NS
L20	4.57	0.16	HS
Q22	1.38	0.04	NS
Q27	5.84	0.30	HS
R41	6.12	0.26	HS
C42	10.63	1.07	HS
K43	1.23	0.89	NS
T44	11.21	1.23	HS
T46	2.07	0.10	WS
S66	0.09	0.09	NS
D76	2.86	0.25	WS
N152	0.94	0.43	NS
F154	0.42	0.23	NS
Y162	4.37	0.18	HS
C163	2.22	0.11	WS
V165	5.29	0.15	HS
R173	4.22	0.32	HS
D174	5.15	0.41	HS
E177	9.52	0.53	HS
Y180	4.85	0.38	HS
R181	7.90	0.57	HS
L184	3.32	0.10	WS
Y185	3.54	0.07	WS
E230	12.47	0.58	HS
F232	−0.02	0.01	NS
R319	5.14	0.71	HS
R327	5.40	0.38	HS