Table 2.
Residues detected on zmGS PPI as a potential HS (buried area ≥ 40 Å2 in at least 6 monomers) with the respective mean value of ΔΔGbind determined by cASM, standard error of mean (SEM) and their classification as HS (red), WS (orange) or NS (yellow).
| Resid | ΔΔGbind | SEM | Classif |
|---|---|---|---|
| C3 | 0.75 | 0.15 | NS |
| L4 | 3.14 | 0.27 | WS |
| D6 | 1.84 | 0.21 | NS |
| L7 | 3.62 | 0.26 | WS |
| V8 | 0.35 | 0.22 | NS |
| L10 | 3.78 | 0.30 | WS |
| L12 | −4.30 | 0.45 | NS |
| T15 | −1.99 | 0.43 | NS |
| I20 | 3.67 | 0.33 | WS |
| R34 | 7.21 | 0.24 | HS |
| T39 | 2.21 | 0.07 | WS |
| D56 | −0.10 | 0.50 | NS |
| S59 | 0.59 | 0.19 | NS |
| E69 | 2.42 | 0.78 | NS |
| R84 | 4.74 | 0.23 | HS |
| F150 | 1.26 | 0.29 | NS |
| Y158 | 3.88 | 0.32 | HS |
| C159 | 1.64 | 0.11 | NS |
| I161 | 7.08 | 0.20 | HS |
| E164 | −1.68 | 0.44 | NS |
| R169 | 8.28 | 0.25 | HS |
| D170 | −1.46 | 0.06 | NS |
| D173 | 5.44 | 0.69 | HS |
| Y176 | 4.07 | 0.20 | HS |
| K177 | 3.39 | 0.40 | WS |
| L180 | 3.91 | 0.23 | WS |
| Y181 | 2.90 | 0.36 | WS |
| E222 | 1.62 | 0.53 | WS |
| R223 | −4.57 | 0.90 | NS |
| E226 | 6.27 | 0.53 | HS |
| I227 | 0.57 | 0.21 | NS |
| N310 | −0.59 | 0.41 | NS |
| R319 | 3.94 | 0.32 | HS |