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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
The hydrogen bond network involving Glu192, Thr132, Ser338, and H2O. Differences in this network switches the chemistry of the active site of M. sativa CHS or P. sylvestris STS between chalcone and stilbene synthesis.