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. 2016 Jun 22;21(6):806. doi: 10.3390/molecules21060806

Scheme 6.

Scheme 6

Bioynthesis of curcuminoids in C. longa. (A) DCS catalyzes the formation of feruloyldiketide-CoA, one of the rare ketides with a CoA still attached to the final product; (B) CURS catalyzes the formation of curcumin from feruloyl-CoA and feruloyldiketide via a rare head-to-head condensation.