Scheme 6.
Bioynthesis of curcuminoids in C. longa. (A) DCS catalyzes the formation of feruloyldiketide-CoA, one of the rare ketides with a CoA still attached to the final product; (B) CURS catalyzes the formation of curcumin from feruloyl-CoA and feruloyldiketide via a rare head-to-head condensation.