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. 2016 Jul 14;21(7):913. doi: 10.3390/molecules21070913

Figure 2.

Figure 2

Figure 2

Typical MRM chromatograms of tetrahydropalmatine(A); palmatine (B); magnoflorine (C); columbamine (D); berberine (E); worenine (F); berberrubine (G); coptisine (H); bifendate (I.S.) in rat plasma: (I) Blank rat plasma; (II) Blank plasma spiked with eight alkaloids and I.S.; (III) a plasma sample from a rat 0.25 h after oral administration of Coptis deltoidea C. Y. cheng et Hsiao (CCY) extract; (IV) a plasma sample from a rat 0.75 h after oral administration of Coptis chinensis Franch (CF) extract.