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. 2016 May 16;21(5):643. doi: 10.3390/molecules21050643

Scheme 2.

Scheme 2

Synthesis of intermediates 1014. Reagents and Conditions: (i) 1-Bromoethanol or 1,2-dibromoethane, K2CO3, acetone, reflux; (ii) substituted benzaldehydes, KOH, EtOH, rt.; (iii) NaOAc, EtOH, 80 °C, reflux.