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Anticonvulsant activities of compounds 6, 7, 8, and 9 in MES test.
 |
| Comp. | R | MES (100 mg/kg) | Toxicity (100 mg/kg) | ||
|---|---|---|---|---|---|
| 0.5 h | 4 h | 0.5 h | 4 h | ||
| 6a | -CH2C6H4 (m-F) | 0/3 | 0/3 | 0/3 | 0/3 |
| 6b | -CH2C6H4 (p-F) | 0/3 | 0/3 | 0/3 | 0/3 |
| 7a | -CH2C6H4 (m-F) | 0/3 | 0/3 | 0/3 | 0/3 |
| 7b | -CH2C6H4 (p-F) | 0/3 | 0/3 | 0/3 | 0/3 |
| 8a | -CH2C6H4 (m-F) | 0/3 | 0/3 | 0/3 | 0/3 |
| 8b | -CH2C6H4 (p-F) | 0/3 | 0/3 | 0/3 | 0/3 |
| 9a | -CH2C6H4 (m-F) | 1/3 | 1/3 | 0/3 | 0/3 |
| 9b | -CH2C6H4 (p-F) | 0/3 | 0/3 | 0/3 | 0/3 |
