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. 2016 Jan 20;21(1):114. doi: 10.3390/molecules21010114

Scheme 2.

Scheme 2

Synthesis of Target compounds 10af and 12ac Reagents and conditions: (i) Neat reaction/reflux 4 h; (ii) Glacial acetic acid/reflux 2 h; (iii) EtOH/reflux 6 h.