2′OMe |
2′-O-methyl |
AO |
antisense oligonucleotides |
DMEM |
Dulbecco’s Modified Eagle Medium |
DMD |
Duchenne muscular dystrophy |
DNA |
deoxyribonucleic acid |
EDTA |
ethylenediaminetetraacetic acid |
FDA |
Food and Drug Administration |
HPLC |
high-performance liquid chromatography |
LCMS |
liquid chromatography-mass spectrometry |
LNA |
locked nucleic acid |
MNA |
morpholino nucleic acid |
MS |
mass spectrometry |
NMR |
nuclear magnetic resonance |
PNA |
peptide nucleic acid |
PMO |
phosphorodiamidate morpholino |
PS |
phosphorothioate |
RNA |
ribonucleic acid |
RT-PCR |
reverse-transcriptase polymerase chain reaction |
UNA |
unlocked nucleic acid |