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IL-11-induced STAT3 activation in a HEK-Blue™ IL-6 cell line transfected with human IL-11Rα gene, monitored by STAT3-induced secretion of SEAP (QUANTI-Blue™ assay) for murine, macaque and human rIL-11. Standard deviations estimated from the duplicate measurements are shown. The dashed curves are theoretical fits to the experimental curves using Boltzmann function.
