Table 1.

Comparison of mixed infection and dominant ribotype across 1) all samples collected and 2) index samples (primary C. difficile infection) in patients who did not recur (nonrecurrent), patients who recurred (subsequent CDI episode in 15–56 days), and patients who were reinfected (subsequent CDI episode > 8 weeks).

Across all samples	Nonrecurrent Patients	Recurrent Patients	Reinfected Patients	All Patients	P
# Patients (% of Total Patients)	20 (32.8)	28 (45.9)	13 (21.3)	61	-
Age, mean (±SD)	58.3 (±20.3)	56.4 (±17.4)	58.6 (±15.7)	55.2 (±18.7)	.89
Female gender, n (%)	10 (50)	18 (64.2)	6 (46.1)	34 (55.7)	.5
PPI use, n (%)	7 (35)	5 (17.9)	3 (25)	15 (24.6)	.4
Prior antibiotic use	7 (35)	6 (21.4)	2 (15.4)	15 (24.6)	.4
Concurrent antibiotics, n (%)	16 (80)	15 (53.6)	7 (53.8)	38 (62)	.1
Mean # samples per patient [IQR]	1.3 [1,1.25]	2.11 [1,3]	1.54 [1,2]	1.72 [1,2]	.00023
Mean # colonies isolated	33.6 [26.3, 40]	35.1 [25, 44]	29.1 [13.5, 40]	33.6 [21, 43]	.48
# samples with mixed infection (% samples in group)	12/26 (46.2)	42/59 (71)	8/20 (40)	62/105 (59)	.015
Mean # of unique ribotypes in samples with mixed infection [IQR]	2.67 [2,3]	2.71 [2,3]	2.25 [2,2]	2.65 [2,3]	.49
Most common dominant ribotype	F014-020	F027	F078-126	F014-020	.38
At Index Sampling (1st documented CDI episode)	Nonrecurrent Patients	Recurrent Patients	Reinfected Patients	All Patients
# Index samples available (% samples in group)	19 (18.1)	14 (13.3)	3 (2.9%)	36 (34.3)	-
# Index samples with mixed infection (% index samples in group)	7/19 (36.8)	11/14 (78.6)	1/3 (33.3)	19/36 (52.8)	.047
Mean # of ribotypes in index samples with mixed infection [IQR]	3 [2,3]	2.38 [2,3]	2 [2,2]	2.57 [2,3]	.59
Most common dominant ribotype (index)	F002	F027	F019	F027	-

P values: Chi-squared test for categorical variables; ANOVA for continuous variables