Key Resources Table

REAGENT or RESOURCE	SOURCE	IDENTIFIER
Chemicals, Peptides, and Recombinant Proteins
mPEG-PLGA (Mw: 2,000:5,000 Da)	Akina	AK090
Propofol	Alfa-Aesar	L06841; CAS: 2078–54–8
Ketamine Hydrochloride	Stanford University Environmental Health & Safety	CAS: 1867–66–9
Tetrahydrofuran (THF)	Sigma-Aldrich	401757; CAS: 109–99–9
Hexane	Sigma-Aldrich	296090; CAS: 110–54–3
n-Perfluoropentane (PFP)	FluoroMed	APF-30M; CAS: 678–26–2
MultiHance Gadobenate Dimeglumine	Bracco Diagnostics	0270–5164; CAS: 127000–20–8
[18F]-Fluorodeoxyglucose (FDG)	Stanford Cyclotron	CAS: 105851–17–0
Microbubbles	Lantheus	Definity (DE4)
IRDye 800RS	LI-COR Biotechnology	IR800
Experimental Models: Organisms/Strains
Rats; Long-Evans Wild-Type	Charles River	Strain ID: 006
Software and Algorithms
Python v3.6	Anaconda	https://www.anaconda.com/download/
ImageJ (Fiji)	Schindelin, J et al., 2012	https://imagej.net/Downloads
Simple ITK Python Package v4.12.12	ITK	https://itk.org/ITK/resources/software.html
Data Acquisition and Analysis code	This paper	Available upon request
Other
Focused Ultrasound System: Integrated Generator, RF Amplifier, Circulation System, and Transducer (2x)	Image Guided Therapy	Custom model
Stereotactic Frame	Image Guided Therapy	Custom model
Bath Sonicator	Thermo Scientific	Bransonic M1800H
Membrane Extruder	Avestin	Liposofast LF-50
Zetasizer	Malvern Panalytical	Zetasizer Nano ZS90
Microtiter Plate Reader	Tecan	Infinite M1000 PRO
Fluorescent Imaging System	Spectral Instruments Imaging	Lago Part #: A1666
3T MRI	MR Solutions	MRS 3017
EEG Recording Board	OpenBCI	Cyton
USB Breakout Board	Adafruit	FT232H
USB Isolator	Adafruit	2107
Green LED	Linrose	B4304H5–10
Raspberry Pi	RS Components Ltd	RPi 2 Model B
PET Scanner	Concorde Microsystems	MicroPET R4