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. 2018 Nov 16;19(11):3616. doi: 10.3390/ijms19113616

Figure 3.

Figure 3

Overexpression of IFT80 enhances the proliferation and invasion potential of SGC-7901 cells, and inhibits apoptosis. (a) Top panel, images represent transfection control of the empty vector, 0 h and 48 h. Bottom panel, SGC-7901, the gastric cancer cells transfected with the IFT80 plasmid at 0 h and 48 h (200×). (b) Cell proliferation is determined by the CCK-8 assay (N = 3, * P < 0.05, control vs. overexpression of ift80). (c) Flow cytometric analysis of apoptotic cells using the annexin V-FITC reagent. Overexpression of IFT80 inhibits apoptosis in SGC-7901 cells. (d) Quantification of images shown in (c). (e) Transwell migration assay analysis the of invasion ability of SGC-7901 gastric cancer cells. IFT80 overexpression promotes the invasion ability of SGC-7901 cells (200×). (f) Quantification of images shown in e. (N = 3, * P < 0.05, control vs. overexpression of ift80).