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. 2018 Nov 15;19(11):3606. doi: 10.3390/ijms19113606

Scheme 1.

Scheme 1

Outline for the synthesis of acetamides (3a3i). Reagents & conditions: N-substituted-2-bromoacetamide (2a2i, one in each case), DMF (N,N-dimethylformamide), LiH (Lithium hydride), sonication for 1 to 1.5 h at RT (Room temperature), “)))” (Ultrasonic radiations).