Table 2.

Observed differences, in terms of p-value as well as not significant (ns) p-value, in each time comparison for steroids and estrogens quantified by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) analyses. First Trimester versus Second Trimester: T1 vs. T2; Second Trimester versus Third Trimester: T2 vs. T3; First Trimester versus Third Trimester: T1 vs. T3; First Trimester versus Post-Partum: T1 vs. P-P; Second Trimester versus Post-Partum: T2 vs. P-P; Third Trimester versus Post-Partum: T3 vs. P-P; Data were obtained by the Kruskal-Wallis test and Dunns’ post hoc test. CORT: Cortisol; CCONE: Corticosterone; 11-DECOL: 11-Deoxycortysol; ADIONE: 4-Androstene-3,17-dione; TESTO: Testosterone; 17-OHP: 17α-hydroxyprogesterone; PROG: Progesterone; E2: Estradiol; E1: Estrone.

Metabolite	ANOVA	T1 vs. T2	T2 vs. T3	T1 vs. T3	T1 vs. P-P	T2 vs. P-P	T3 vs. P-P
CORT	<0.0001	<0.01	ns	<0.05	ns	<0.0001	<0.0001
CCONE	<0.001	ns	ns	<0.05	ns	<0.05	<0.01
11-DECOL	<0.01	ns	ns	ns	ns	<0.01	<0.05
ADIONE	<0.005	ns	ns	ns	<0.05	<0.01	ns
TESTO	<0.0001	ns	ns	ns	<0.01	<0.0001	<0.01
17-OHP	<0.0001	ns	ns	ns	<0.05	<0.0001	<0.0001
PROG	<0.0001	ns	ns	<0.01	ns	<0.0001	<0.0001
E2	<0.0001	ns	ns	<0.01	ns	<0.0001	<0.0001
E1	<0.0001	ns	ns	ns	ns	<0.0001	<0.0001