Table 2.
Differentially Methylated Genes | |||
---|---|---|---|
Methylation State | Gene Position | Gene Hits | Genes Identified |
Hypermethylated | Upstream | 36 | |
Inside | 291 | ||
Downstream | 134 | ||
Total | 461 | 423 | |
Hypomethylated | Upstream | 19 | |
Inside | 201 | ||
Downstream | 80 | ||
Total | 300 | 281 | |
Equally-methylated | Upstream | 6 | |
Inside | 41 | ||
Downstream | 8 | ||
Total | 55 | 27 | |
Total DMGs | 816 | 731 |
The methylation state refers to the number of 5′ Methylated Cytosines (5mCs) in ‘Desmayo Largueta’ samples compared to ‘Penta’ samples. The category “equally methylated” refers to genes whose number of 5mCs was the same between samples but in which the 5mCs were located in different fragment positions. The gene position is based on gene orientation with respect to the fragment-mapping region (“upstream”, “inside”, and “downstream”).