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Effects of AEO on restraint stress-induced anxiety as assessed by the open field (OF) test. All mice except for the naive group received 10 days restraint stress, then (A) time spent and (B) distance moved in the central area were recorded over a 10 min session. Each value represents mean ± SEM with n = 12, ## p < 0.01 vs. the naive group, * p < 0.05 and ** p < 0.01 vs. the stressed group.
