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. 2018 Oct 26;19(11):3352. doi: 10.3390/ijms19113352

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Photomicrographs of the morphological changes observed in control, Selenite, Bevacizumab (BV), Selenobevacizumab (Se-BV), Trastuzumab (TZ) and Selenotrastuzumab-Treated MDA-MB-468 Cells. Treatment of the MDA-MB-468 Cells with Selenite, Se-BV and Se-TZ revealed morphological changes indicative of membrane disruption and decreased cell viability in comparison to the native antibodies BV and TZ. Representative fields of view of MDA-MB-468 cells. Cells were photographed under phase contrast conditions at 20× magnification. Scale bar = 100 µm.