Effect of oral administration of collagen peptide on TEWL, hydration, and epidermal thickness in the dorsal skin of UVB-irradiated hairless mice. (A) Body weight changes, (B) TEWL, and (C) stratum corneum water content after repeated irradiation with UVB were measured using the Derma Combo System; (D) hematoxylin and eosin staining. Scale bar = 100 μm. Arrows indicate the thickness of epidermis; (E) histogram of hematoxylin and eosin staining. The values are shown as mean ± SEM (n = 8). ### p < 0.001 (vs. control mice). * p < 0.05, ** p < 0.01, and *** p < 0.001 (vs. UVB-irradiated mice).