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. 2018 Oct 29;19(11):3381. doi: 10.3390/ijms19113381

Figure 3.

Figure 3

miR-221-5p inhibits PEDV replication in IECs and Vero cells. Real-time qRT-PCR analysis of intracellular viral genomic RNA (normalized to β-actin expression). IECs were transfected with miR-221-5p mimics (A) or inhibitor (B) at 50 nM for 12 h, followed by infection with PEDV CV777 for an additional 36 h. Vero cells were transfected with miR-221-5p mimics (C) or inhibitor (D) at 50 nM for 12 h, followed by infection with PEDV CH/HBTS/2017 for an additional 36 h. Data represent the mean ± SD of three independent experiments and measured in technical duplicate. Comparisons between groups were determined by Student’s t test. * p < 0.05; ** p < 0.01.