Akt	Protein kinase B
CR	Coptidis Rhizoma
CRP	C-reactive protein
ERK	Extracellular regulated protein kinases
FBG	Fasting blood glucose
FBPase	Fructose-1,6-bisphosphatase
FFA	Free fatty acid
FINS	Fasting insulin
G6Pase	Glucose 6-phosphatase
GK	Glucokinase
Glut 2	Glucose transporter 2
GP	Glycogen phosphorylase
GS	Glycogen synthase
HDL-C	High-density lipoprotein
HFD	High-fat diet
HSC	How dose of combined extracts group
IFN-γ	Interferon gamma
IKK	Inhibitor of nuclear factor kappa-B kinase
IL-1β	Interleukin 1β
IL-6	Interleukin 6
IRS1	Insulin receptor substrate 1
JNK	C-Jun N-terminal kinase
LDL-C	Low-density lipoprotein
LSC	Low dose of combined extracts group
MAPK	Mitogen-activated protein kinase
NO	Nitric oxide
P	Metformin
P38	P38 mitogen-activated protein kinases
PEPCK	Phosphoenolpyruvate carboxykinase
PFK	Phosphofructokinase
PI3K	Phosphatidylinositol-4,5-bisphosphate 3-kinase
PK	Pyruvate kinase
SOCS3	Suppressor of cytokine signaling 3
SR	Scutellariae Radix
STZ	Streptozocin
T2DM	Type 2 diabetes mellitus
TC	Total chelosterol
TCM	Traditional Chinese medicine
TG	Triglyceride
TNF-α	Tumor necrosis factor alpha
UPLC-Q-TOF/MS	Ultra performance liquid chromatography-quadrupole time-of-flight mass spectrometry