ROS |
Reactive oxygen species |
NADPH |
Nicotinamide adenine dinucleotide phosphate |
RPE |
Retinal pigment epithelium |
DNA |
Deoxyribonucleic acid |
RNA |
Ribonucleic acid |
IOP |
Intraocular pressure |
RGC |
Retinal ganglion cell |
TM |
Trabecular meshwork |
NMDA |
N-methyl-D-aspartate |
NO |
Nitric oxide |
SkQ1 |
10-(6′-pastioquinonyl) decyltriphenylphosphonium |
ATP |
Adenosine triphosphate |
TNF-α |
Tumor necrosis factor-alpha |
H2O2
|
Hydrogen peroxide |
SOD |
Superoxide dismutase |
HO |
Heme oxygenase |
GSH |
Glutathione |
Nrf2 |
Nuclear factor erythroid-derived 2 |
ASK1 |
Apoptosis signal-regulating kinase 1 |
NAC |
N-acetylcysteine |
Dock3 |
Dedicator of cytokinesis 3 |
DR |
Diabetic retinopathy |
PKC |
Protein kinase C |
AGE |
Advanced glycation end product |
RAGE |
Receptor for advanced glycation end products |
PEDF |
Pigment epithelium-derived growth factor |
mRNA |
Messenger RNA |
PI3K |
Phosphoinositide 3-kinase |
Akt |
Protein kinase B |
VEGF |
Vascular endothelial growth factor |
HIF |
Hypoxia-inducible factor |
IL |
Interleukin |
LDL |
Low-density lipoprotein |
CoCl2
|
Cobalt chloride |
NADH |
Nicotinamide adenine dinucleotide |
NFAT |
Nuclear factor of activated T cells |
BRB |
Blood-retinal barrier |
MMP |
Matrix metalloproteinase |
ICAM-1 |
Intercellular adhesion molecule 1 |
siRNA |
Small interfering RNA |
AMD |
Age-related macular degeneration |
CNV |
Choroidal neovascularization |
Bcl-2 |
B-cell lymphoma 2 |
MAPK |
Mitogen-activated protein kinase |
JNK |
Jun NH2-terminal kinase |
MnTMPyP |
Manganese (III) tetrakis(1-methyl-4-pyridyl)porphyrin |
Hsp27 |
Heat shock protein 27 |
FAK |
Focal adhesion kinase |
BSIH |
Isonicotinic acid [2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzylidene]-Hydrazide |
SIH |
Salicylaldehyde isonicotinoyl |
PF-4/CXCL4 |
Platelet factor-4 |