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. 2018 Nov 16;19(11):3622. doi: 10.3390/ijms19113622

Figure 2.

Figure 2

Inhibition of nitric oxide (NO) production (a) Inducible nitric oxide synthase (iNOS) protein expression in LPS (1 µg/mL)-induced Raw 264.7 cells pre-treated with 100 and 200 µg/mL solvent fractions (HEX—hexane; DICHO—dichloromethane; EA—ethyl acetate; BUT—butanol) of Geranium koreanum extracts for 24 h in 5% CO2 incubator. NO production was measured using the Griess assay and the expression of iNOS protein was analyzed using the Western blotting assay. Data are means ± standard deviation (SD); ### p < 0.001 compared with normal control cells; *** p < 0.001 compared with LPS control cells.