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. 2018 Nov 16;19(11):3622. doi: 10.3390/ijms19113622

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Image of gross esophageal erosions area (a) and esophageal mucosal ulcer ratio (b) of acute RE rats. Normal—untreated rats; reflux esophagitis (RE) Control—RE rats; RE + DGK100—DICHO fraction of Geranium koreanum 100 mg/kg body weight treated RE rats; RE + DGK 200—DICHO fraction of Geranium koreanum 200 mg/kg body weight treated RE rats. The incidence of erosions area was significantly decreased in rats treated with DGK. Data are means ± standard deviation (SD); ^## p < 0.01 and * p < 0.05 compared with normal control and RE control groups, respectively.

Image of gross esophageal erosions area (a) and esophageal mucosal ulcer ratio (b) of acute RE rats. Normal—untreated rats; reflux esophagitis (RE) Control—RE rats; RE + DGK100—DICHO fraction of Geranium koreanum 100 mg/kg body weight treated RE rats; RE + DGK 200—DICHO fraction of Geranium koreanum 200 mg/kg body weight treated RE rats. The incidence of erosions area was significantly decreased in rats treated with DGK. Data are means ± standard deviation (SD); ^## p < 0.01 and * p < 0.05 compared with normal control and RE control groups, respectively.